STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ETV5ETS variant 5. (510 aa)    
Predicted Functional Partners:
COP1
COP1 E3 ubiquitin ligase.
    
 
 0.871
DET1
Uncharacterized protein.
    
 
 0.831
STK40
Serine/threonine kinase 40.
   
   0.823
SLC45A3
Solute carrier family 45 member 3.
   
  
 0.619
G3S285_GORGO
Uncharacterized protein.
   
  
 0.582
G3SIN0_GORGO
Uncharacterized protein.
   
  
 0.582
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
   
 0.547
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
      
 0.540
RUNX2
Runt domain-containing protein.
   
 0.532
BCL6B
BCL6B transcription repressor.
    
 
 0.513
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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