STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PEG3Paternally-expressed gene 3 protein; Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Belongs to the krueppel C2H2-type zinc-finger protein family. (1463 aa)    
Predicted Functional Partners:
MEST
Mesoderm specific transcript.
   
 
 0.808
SNRPN
Small nuclear ribonucleoprotein-associated protein.
     
 0.677
PLAGL1
PLAG1 like zinc finger 1.
      
 0.649
GRB10
Growth factor receptor bound protein 10.
    
 0.573
GNAS
GNAS complex locus.
      
 0.568
NLRP7
NLR family pyrin domain containing 7.
     
 0.567
DLK1
Delta like non-canonical Notch ligand 1.
   
 0.510
CDKN1C
Cyclin dependent kinase inhibitor 1C.
   
 
 0.492
ENSGGOP00000048475
PHD-type domain-containing protein.
   
 0.474
IGF2
Insulin like growth factor 2.
      
 0.461
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.