STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HAND2Heart and neural crest derivatives expressed 2. (198 aa)    
Predicted Functional Partners:
G3R5D7_GORGO
Uncharacterized protein.
   
 0.848
NKX2-5
NK2 homeobox 5.
   
 
 0.844
RUNX2
Runt domain-containing protein.
    
 0.760
G3RWH6_GORGO
Transcription factor 3.
   
 0.718
TBX5
T-box transcription factor 5.
   
 0.716
ENSGGOP00000031261
Myocyte enhancer factor 2C.
    
 
 0.681
TBX20
T-box transcription factor 20.
   
  
 0.678
MYOCD
Myocardin.
   
  
 0.667
GATA6
GATA binding protein 6.
   
 0.656
ISL1
ISL LIM homeobox 1.
    
 0.633
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.