STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (753 aa)    
Predicted Functional Partners:
POMC
Proopiomelanocortin.
     
 0.838
GCG
Glucagon.
     
 0.764
INS
Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.746
GHRL
Ghrelin and obestatin prepropeptide.
     
 0.692
RIPK3
Receptor interacting serine/threonine kinase 3.
   
 0.685
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.685
CPE
Carboxypeptidase E.
   
  
 0.679
NHLH2
Nescient helix-loop-helix 2.
      
 0.672
PCSK1N
Proprotein convertase subtilisin/kexin type 1 inhibitor.
    
 
 0.664
MLKL
Uncharacterized protein.
   
 0.662
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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