STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK2Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family. (638 aa)    
Predicted Functional Partners:
SCG5
Secretogranin V.
   
 
 0.856
INS
Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.727
CPE
Carboxypeptidase E.
   
  
 0.615
POMC
Proopiomelanocortin.
     
 0.607
MAPK8IP2
Mitogen-activated protein kinase 8 interacting protein 2.
   
  
 0.580
GCG
Glucagon.
   
 
 0.573
RESP18
Regulated endocrine specific protein 18.
   
  
 0.526
PTPRN
Protein tyrosine phosphatase receptor type N.
   
  
 0.526
ENSGGOP00000047807
Protein tyrosine phosphatase receptor type N2.
   
  
 0.526
SST
Somatostatin.
   
  
 0.522
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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