STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADGRG1Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...] (693 aa)    
Predicted Functional Partners:
GNA13
G protein subunit alpha 13.
    
 
 0.880
GNA12
G protein subunit alpha 12.
    
 
 0.813
GNB1
G protein subunit beta 1.
   
   0.764
GNG2
G protein gamma domain-containing protein.
    
   0.760
PDGFD
Platelet derived growth factor D.
      
 0.704
TGM2
Transglutaminase 2.
   
  
 0.675
G3RNC1_GORGO
Myosin light chain 10.
      
 0.622
NEUROG1
Neurogenin 1.
      
 0.622
FABP7
Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
      
 0.609
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
      
 0.584
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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