STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)    
Predicted Functional Partners:
HEY2
Orange domain-containing protein.
    
0.988
HEYL
Hes related family bHLH transcription factor with YRPW motif like.
  
  
0.949
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 
 0.828
NOTCH1
Uncharacterized protein.
    
 0.818
CUL1
Cullin domain-containing protein; Belongs to the cullin family.
    
 
 0.812
HES1
Hes family bHLH transcription factor 1.
    
0.805
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.739
NOTCH4
Notch receptor 4.
   
 0.729
NT5C1B
Uncharacterized protein.
    
 
 0.717
RUNX2
Runt domain-containing protein.
    
 0.699
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.