STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR50G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family. (628 aa)    
Predicted Functional Partners:
MTNR1B
Melatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family.
    
0.916
MTNR1A
Melatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family.
    
0.913
ARRB2
Arrestin beta 2.
   
 0.603
KRT74
Keratin 74; Belongs to the intermediate filament family.
      
 0.561
CD99L2
CD99 molecule like 2.
      
 0.530
TRH
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
  
  
 0.477
CPB1
Carboxypeptidase B1.
     
 0.470
ENSGGOP00000034118
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
  
  
 0.441
NPL
Uncharacterized protein.
      
 0.440
ENSGGOP00000049973
Fas activated serine/threonine kinase.
  
   
 0.439
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.