STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGM2Transglutaminase 2. (687 aa)    
Predicted Functional Partners:
ADGRG1
Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]
   
  
 0.675
TOR1A
Torsin.
      
 0.674
RHAG
Ammonium transporter Rh type A; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
   
 
 0.622
TSG101
Tumor susceptibility 101.
   
  
 0.601
G3SB50_GORGO
Protein C, inactivator of coagulation factors Va and VIIIa.
     
 0.526
ARNT
Aryl hydrocarbon receptor nuclear translocator.
    
 
 0.521
F13B
Coagulation factor XIII B chain.
    
 0.517
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.516
IVL
Involucrin_N domain-containing protein.
    
 0.506
SBSN
Suprabasin.
   
 0.501
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.