STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZFYZinc finger Y-chromosomal protein; Probable transcriptional activator. Binds to the consensus sequence 5'-AGGCCY-3' (By similarity). (841 aa)    
Predicted Functional Partners:
DCTN2
Dynactin subunit 2.
    
 
 0.850
RPS4Y1
40S ribosomal protein S4, Y isoform 1; Belongs to the eukaryotic ribosomal protein eS4 family.
   
 0.807
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
      
 0.807
POLA1
DNA polymerase.
   
 
 0.789
NLGN3
Neuroligin 3.
   
 0.717
PRKX
Protein kinase X-linked; Belongs to the protein kinase superfamily.
   
 0.707
PCDH11X
Protocadherin-11 X-linked; Potential calcium-dependent cell-adhesion protein.
   
 
 0.698
MYCN
MYCN proto-oncogene, bHLH transcription factor.
    
 0.689
ENSGGOP00000048897
Uncharacterized protein.
      
 0.672
G3S4D8_GORGO
Lysine demethylase 6A.
   
 0.662
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.