STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (551 aa)    
Predicted Functional Partners:
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
   
 0.998
IFIT1
Interferon induced protein with tetratricopeptide repeats 1.
   
 0.983
G3RG63_GORGO
ISG15 ubiquitin like modifier.
   
 
 0.977
DNAJC3
DnaJ heat shock protein family (Hsp40) member C3.
   
 0.974
RIPK1
Receptor interacting serine/threonine kinase 1.
  
0.960
DDX58
DExD/H-box helicase 58.
   
 0.953
CHUK
IKKbetaNEMObind domain-containing protein.
   
 0.952
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
  
0.948
IRS1
Insulin receptor substrate 1.
    
 0.948
PRKRA
Protein activator of interferon induced protein kinase EIF2AK2.
    
 
 0.947
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (22%) [HD]