STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIPProlactin-inducible protein homolog; Belongs to the PIP family. (146 aa)    
Predicted Functional Partners:
G3QHX6_GORGO
Alpha-2-glycoprotein 1, zinc-binding; Belongs to the MHC class I family.
   
 0.988
G3RRN0_GORGO
Ig-like domain-containing protein; Belongs to the MHC class I family.
   
 0.988
DSG1
Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
      
 0.836
IL1RL2
Interleukin 1 receptor like 2.
      
 0.822
ACP3
Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family.
      
 0.731
KRT7
Keratin 7; Belongs to the intermediate filament family.
    
 
 0.669
SCGB2A2
Secretoglobin family 2A member 2.
  
  
 0.659
KRT20
Keratin 20; Belongs to the intermediate filament family.
    
 
 0.657
C17H17orf97
Uncharacterized protein.
    
 
 0.618
ANG
Angiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (By similarity). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity).
      
 0.595
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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