node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACP3 | ANG | ENSGGOP00000012592 | ENSGGOP00000035667 | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. | Angiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (By similarity). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity). | 0.455 |
ACP3 | DSG1 | ENSGGOP00000012592 | ENSGGOP00000000137 | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | 0.687 |
ACP3 | G3QHX6_GORGO | ENSGGOP00000012592 | ENSGGOP00000001964 | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. | Alpha-2-glycoprotein 1, zinc-binding; Belongs to the MHC class I family. | 0.537 |
ACP3 | IL1RL2 | ENSGGOP00000012592 | ENSGGOP00000003293 | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. | Interleukin 1 receptor like 2. | 0.681 |
ACP3 | PIP | ENSGGOP00000012592 | ENSGGOP00000021000 | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. | Prolactin-inducible protein homolog; Belongs to the PIP family. | 0.731 |
ANG | ACP3 | ENSGGOP00000035667 | ENSGGOP00000012592 | Angiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (By similarity). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity). | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. | 0.455 |
ANG | DSG1 | ENSGGOP00000035667 | ENSGGOP00000000137 | Angiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (By similarity). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity). | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | 0.575 |
ANG | IL1RL2 | ENSGGOP00000035667 | ENSGGOP00000003293 | Angiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (By similarity). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity). | Interleukin 1 receptor like 2. | 0.622 |
ANG | PIP | ENSGGOP00000035667 | ENSGGOP00000021000 | Angiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (By similarity). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity). | Prolactin-inducible protein homolog; Belongs to the PIP family. | 0.595 |
C17H17orf97 | KRT7 | ENSGGOP00000009531 | ENSGGOP00000006457 | Uncharacterized protein. | Keratin 7; Belongs to the intermediate filament family. | 0.770 |
C17H17orf97 | PIP | ENSGGOP00000009531 | ENSGGOP00000021000 | Uncharacterized protein. | Prolactin-inducible protein homolog; Belongs to the PIP family. | 0.618 |
DSG1 | ACP3 | ENSGGOP00000000137 | ENSGGOP00000012592 | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. | 0.687 |
DSG1 | ANG | ENSGGOP00000000137 | ENSGGOP00000035667 | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | Angiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (By similarity). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity). | 0.575 |
DSG1 | IL1RL2 | ENSGGOP00000000137 | ENSGGOP00000003293 | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | Interleukin 1 receptor like 2. | 0.917 |
DSG1 | PIP | ENSGGOP00000000137 | ENSGGOP00000021000 | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | Prolactin-inducible protein homolog; Belongs to the PIP family. | 0.836 |
G3QHX6_GORGO | ACP3 | ENSGGOP00000001964 | ENSGGOP00000012592 | Alpha-2-glycoprotein 1, zinc-binding; Belongs to the MHC class I family. | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. | 0.537 |
G3QHX6_GORGO | G3RRN0_GORGO | ENSGGOP00000001964 | ENSGGOP00000018454 | Alpha-2-glycoprotein 1, zinc-binding; Belongs to the MHC class I family. | Ig-like domain-containing protein; Belongs to the MHC class I family. | 0.545 |
G3QHX6_GORGO | PIP | ENSGGOP00000001964 | ENSGGOP00000021000 | Alpha-2-glycoprotein 1, zinc-binding; Belongs to the MHC class I family. | Prolactin-inducible protein homolog; Belongs to the PIP family. | 0.988 |
G3RRN0_GORGO | G3QHX6_GORGO | ENSGGOP00000018454 | ENSGGOP00000001964 | Ig-like domain-containing protein; Belongs to the MHC class I family. | Alpha-2-glycoprotein 1, zinc-binding; Belongs to the MHC class I family. | 0.545 |
G3RRN0_GORGO | PIP | ENSGGOP00000018454 | ENSGGOP00000021000 | Ig-like domain-containing protein; Belongs to the MHC class I family. | Prolactin-inducible protein homolog; Belongs to the PIP family. | 0.988 |