STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOPAZ1Protein TOPAZ1; Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear. (1664 aa)    
Predicted Functional Partners:
G3R6Z2_GORGO
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
   
 0.657
TUBGCP6
Tubulin gamma complex associated protein 6.
   
 0.657
ENSGGOP00000044919
Uncharacterized protein.
   
 0.645
TUBGCP5
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
   
 0.645
TUBGCP2
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
   
 0.618
TUBGCP4
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
    
 0.605
G3QWD6_GORGO
Tubulin delta 1; Belongs to the tubulin family.
   
 0.554
ENSGGOP00000043781
Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.
   
 0.554
ENSGGOP00000037283
Propionyl-CoA carboxylase subunit beta.
   
 
 0.551
MCCC2
Methylcrotonoyl-CoA carboxylase 2.
   
 
 0.551
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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