STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
101132169Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction (138 aa)    
Predicted Functional Partners:
DMRT1
Doublesex and mab-3 related transcription factor 1
   
  
 0.924
TNP1
Transition protein 1 (during histone to protamine replacement)
   
  
 0.847
PRM2
Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex
   
  
 0.835
PRM3
Protamine 3
   
  
 0.810
NR0B1
Nuclear receptor subfamily 0, group B, member 1
   
  
 0.747
RHOXF1
Rhox homeobox family, member 1
      
 0.685
SPATA19
Spermatogenesis associated 19
   
  
 0.679
TCP11
T-complex 11, testis-specific
   
  
 0.671
SPATA24
Uncharacterized protein
      
 0.663
SPATA33
Spermatogenesis associated 33
   
  
 0.635
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Gorilla gorilla, gorilla, western gorilla
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