Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGRP | ASIP | ENSGGOP00000012662 | ENSGGOP00000026258 | Agouti related neuropeptide. | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | 0.611 |
| AGRP | ATRN | ENSGGOP00000012662 | ENSGGOP00000026184 | Agouti related neuropeptide. | Attractin. | 0.455 |
| AGRP | POMC | ENSGGOP00000012662 | ENSGGOP00000003417 | Agouti related neuropeptide. | Proopiomelanocortin. | 0.871 |
| ASIP | AGRP | ENSGGOP00000026258 | ENSGGOP00000012662 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Agouti related neuropeptide. | 0.611 |
| ASIP | ATRN | ENSGGOP00000026258 | ENSGGOP00000026184 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Attractin. | 0.600 |
| ASIP | G3QQG6_GORGO | ENSGGOP00000026258 | ENSGGOP00000004832 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | SET domain and mariner transposase fusion gene. | 0.913 |
| ASIP | OCA2 | ENSGGOP00000026258 | ENSGGOP00000005781 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | OCA2 melanosomal transmembrane protein. | 0.612 |
| ASIP | POMC | ENSGGOP00000026258 | ENSGGOP00000003417 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Proopiomelanocortin. | 0.673 |
| ASIP | RALY | ENSGGOP00000026258 | ENSGGOP00000022369 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | RALY heterogeneous nuclear ribonucleoprotein. | 0.606 |
| ASIP | SLC45A2 | ENSGGOP00000026258 | ENSGGOP00000004723 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Solute carrier family 45 member 2. | 0.570 |
| ASIP | SRP14 | ENSGGOP00000026258 | ENSGGOP00000009688 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Uncharacterized protein. | 0.658 |
| ASIP | SRP9 | ENSGGOP00000026258 | ENSGGOP00000011270 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. | 0.686 |
| ASIP | TYR | ENSGGOP00000026258 | ENSGGOP00000008910 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. | 0.588 |
| ATRN | AGRP | ENSGGOP00000026184 | ENSGGOP00000012662 | Attractin. | Agouti related neuropeptide. | 0.455 |
| ATRN | ASIP | ENSGGOP00000026184 | ENSGGOP00000026258 | Attractin. | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | 0.600 |
| ATRN | TYR | ENSGGOP00000026184 | ENSGGOP00000008910 | Attractin. | Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. | 0.461 |
| G3QQG6_GORGO | ASIP | ENSGGOP00000004832 | ENSGGOP00000026258 | SET domain and mariner transposase fusion gene. | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | 0.913 |
| G3QQG6_GORGO | POMC | ENSGGOP00000004832 | ENSGGOP00000003417 | SET domain and mariner transposase fusion gene. | Proopiomelanocortin. | 0.473 |
| G3QQG6_GORGO | SRP14 | ENSGGOP00000004832 | ENSGGOP00000009688 | SET domain and mariner transposase fusion gene. | Uncharacterized protein. | 0.617 |
| G3QQG6_GORGO | SRP9 | ENSGGOP00000004832 | ENSGGOP00000011270 | SET domain and mariner transposase fusion gene. | Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. | 0.796 |
page 1 of 3