node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APOBEC3G | C1H1orf198 | ENSGGOP00000021965 | ENSGGOP00000006425 | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] | Chromosome 1 open reading frame 198. | 0.851 |
APOBEC3G | CBFB | ENSGGOP00000021965 | ENSGGOP00000049062 | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] | Core-binding factor subunit beta. | 0.860 |
APOBEC3G | CUL5 | ENSGGOP00000021965 | ENSGGOP00000027637 | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] | Cullin 5; Belongs to the cullin family. | 0.976 |
APOBEC3G | ELOB | ENSGGOP00000021965 | ENSGGOP00000014931 | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] | Elongin B. | 0.964 |
APOBEC3G | ELOC | ENSGGOP00000021965 | ENSGGOP00000002153 | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] | Elongin C; Belongs to the SKP1 family. | 0.951 |
APOBEC3G | G3QFP8_GORGO | ENSGGOP00000021965 | ENSGGOP00000001126 | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] | Cytochrome c oxidase subunit 5B. | 0.851 |
APOBEC3G | G3QV16_GORGO | ENSGGOP00000021965 | ENSGGOP00000006577 | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] | Apolipoprotein B mRNA editing enzyme catalytic subunit 3B. | 0.921 |
APOBEC3G | G3R2E6_GORGO | ENSGGOP00000021965 | ENSGGOP00000009396 | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. | 0.922 |
APOBEC3G | G3RZU2_GORGO | ENSGGOP00000021965 | ENSGGOP00000021335 | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] | Cytochrome c1. | 0.848 |
APOBEC3G | RNF7 | ENSGGOP00000021965 | ENSGGOP00000001803 | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] | Ring finger protein 7. | 0.947 |
C1H1orf198 | APOBEC3G | ENSGGOP00000006425 | ENSGGOP00000021965 | Chromosome 1 open reading frame 198. | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] | 0.851 |
C1H1orf198 | G3QV16_GORGO | ENSGGOP00000006425 | ENSGGOP00000006577 | Chromosome 1 open reading frame 198. | Apolipoprotein B mRNA editing enzyme catalytic subunit 3B. | 0.851 |
C1H1orf198 | G3RZU2_GORGO | ENSGGOP00000006425 | ENSGGOP00000021335 | Chromosome 1 open reading frame 198. | Cytochrome c1. | 0.966 |
CBFB | APOBEC3G | ENSGGOP00000049062 | ENSGGOP00000021965 | Core-binding factor subunit beta. | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] | 0.860 |
CBFB | CUL5 | ENSGGOP00000049062 | ENSGGOP00000027637 | Core-binding factor subunit beta. | Cullin 5; Belongs to the cullin family. | 0.995 |
CBFB | ELOB | ENSGGOP00000049062 | ENSGGOP00000014931 | Core-binding factor subunit beta. | Elongin B. | 0.984 |
CBFB | ELOC | ENSGGOP00000049062 | ENSGGOP00000002153 | Core-binding factor subunit beta. | Elongin C; Belongs to the SKP1 family. | 0.921 |
CBFB | G3QV16_GORGO | ENSGGOP00000049062 | ENSGGOP00000006577 | Core-binding factor subunit beta. | Apolipoprotein B mRNA editing enzyme catalytic subunit 3B. | 0.548 |
CBFB | G3R2E6_GORGO | ENSGGOP00000049062 | ENSGGOP00000009396 | Core-binding factor subunit beta. | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. | 0.901 |
CBFB | RNF7 | ENSGGOP00000049062 | ENSGGOP00000001803 | Core-binding factor subunit beta. | Ring finger protein 7. | 0.938 |