STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APOBEC3GDNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] (376 aa)    
Predicted Functional Partners:
CUL5
Cullin 5; Belongs to the cullin family.
     
 0.976
ELOB
Elongin B.
   
 
 0.964
ELOC
Elongin C; Belongs to the SKP1 family.
     
 0.951
RNF7
Ring finger protein 7.
   
 0.947
G3R2E6_GORGO
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
     
 0.922
G3QV16_GORGO
Apolipoprotein B mRNA editing enzyme catalytic subunit 3B.
  
0.921
CBFB
Core-binding factor subunit beta.
    
 
 0.860
G3QFP8_GORGO
Cytochrome c oxidase subunit 5B.
   
 0.851
C1H1orf198
Chromosome 1 open reading frame 198.
   
 0.851
G3RZU2_GORGO
Cytochrome c1.
   
 0.848
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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