STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRAFB-Raf proto-oncogene, serine/threonine kinase. (766 aa)    
Predicted Functional Partners:
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
  
 
0.998
NRAS
NRAS proto-oncogene, GTPase.
   
 0.998
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
0.997
HRAS
HRas proto-oncogene, GTPase.
   
 0.997
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
  
 
0.996
MAP2K2
Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.
   
0.995
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
   
 0.994
RAP1A
RAP1A, member of RAS oncogene family.
   
 0.978
KRAS
KRAS proto-oncogene, GTPase.
   
 0.977
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.
   
 0.975
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.