node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IKBKG | IRAK1 | ENSPPAP00000004543 | ENSPPAP00000034763 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Interleukin 1 receptor associated kinase 1. | 0.997 |
IKBKG | IRAK2 | ENSPPAP00000004543 | ENSPPAP00000031279 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Interleukin 1 receptor associated kinase 2. | 0.851 |
IKBKG | IRAK4 | ENSPPAP00000004543 | ENSPPAP00000009286 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Interleukin 1 receptor associated kinase 4. | 0.999 |
IKBKG | LOC100986336 | ENSPPAP00000004543 | ENSPPAP00000004282 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | TIR domain-containing protein. | 0.468 |
IKBKG | MYD88 | ENSPPAP00000004543 | ENSPPAP00000029064 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | 0.997 |
IKBKG | TLR5 | ENSPPAP00000004543 | ENSPPAP00000001949 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Toll-like receptor 5; Belongs to the Toll-like receptor family. | 0.422 |
IKBKG | TLR7 | ENSPPAP00000004543 | ENSPPAP00000009572 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Toll-like receptor 7; Belongs to the Toll-like receptor family. | 0.518 |
IKBKG | TRAF6 | ENSPPAP00000004543 | ENSPPAP00000040651 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.999 |
IL1R1 | IRAK1 | ENSPPAP00000033001 | ENSPPAP00000034763 | Interleukin 1 receptor type 1. | Interleukin 1 receptor associated kinase 1. | 0.998 |
IL1R1 | IRAK2 | ENSPPAP00000033001 | ENSPPAP00000031279 | Interleukin 1 receptor type 1. | Interleukin 1 receptor associated kinase 2. | 0.856 |
IL1R1 | IRAK4 | ENSPPAP00000033001 | ENSPPAP00000009286 | Interleukin 1 receptor type 1. | Interleukin 1 receptor associated kinase 4. | 0.986 |
IL1R1 | LOC100986336 | ENSPPAP00000033001 | ENSPPAP00000004282 | Interleukin 1 receptor type 1. | TIR domain-containing protein. | 0.616 |
IL1R1 | MYD88 | ENSPPAP00000033001 | ENSPPAP00000029064 | Interleukin 1 receptor type 1. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | 0.999 |
IL1R1 | TIRAP | ENSPPAP00000033001 | ENSPPAP00000001223 | Interleukin 1 receptor type 1. | TIR domain-containing protein. | 0.703 |
IL1R1 | TLR5 | ENSPPAP00000033001 | ENSPPAP00000001949 | Interleukin 1 receptor type 1. | Toll-like receptor 5; Belongs to the Toll-like receptor family. | 0.672 |
IL1R1 | TLR7 | ENSPPAP00000033001 | ENSPPAP00000009572 | Interleukin 1 receptor type 1. | Toll-like receptor 7; Belongs to the Toll-like receptor family. | 0.566 |
IL1R1 | TRAF6 | ENSPPAP00000033001 | ENSPPAP00000040651 | Interleukin 1 receptor type 1. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.996 |
IRAK1 | IKBKG | ENSPPAP00000034763 | ENSPPAP00000004543 | Interleukin 1 receptor associated kinase 1. | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | 0.997 |
IRAK1 | IL1R1 | ENSPPAP00000034763 | ENSPPAP00000033001 | Interleukin 1 receptor associated kinase 1. | Interleukin 1 receptor type 1. | 0.998 |
IRAK1 | IRAK2 | ENSPPAP00000034763 | ENSPPAP00000031279 | Interleukin 1 receptor associated kinase 1. | Interleukin 1 receptor associated kinase 2. | 0.994 |