STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIM1Single-minded homolog 1; Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult. (767 aa)    
Predicted Functional Partners:
ARNT2
Uncharacterized protein.
    
 
0.859
ARNT
Aryl hydrocarbon receptor nuclear translocator.
    
 
0.759
UBE2V2
UBIQUITIN_CONJUGAT_2 domain-containing protein.
      
 0.701
OTP
Orthopedia homeobox.
   
  
 0.681
NR4A2
Nuclear receptor subfamily 4 group A member 2.
      
 0.674
APLF
Aprataxin and PNKP like factor.
      
 0.657
MC4R
Melanocortin 4 receptor.
      
 0.654
PIAS1
Protein inhibitor of activated STAT 1.
      
 0.652
MCHR2
Melanin concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.646
SAE1
SUMO1 activating enzyme subunit 1.
   
  
 0.613
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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