node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IFI27 | IFI44 | ENSPTRP00000011379 | ENSPTRP00000001546 | Interferon, alpha-inducible protein 27. | Interferon-induced protein 44; This protein aggregates to form microtubular structures; Belongs to the IFI44 family. | 0.928 |
IFI27 | IFIH1 | ENSPTRP00000011379 | ENSPTRP00000021498 | Interferon, alpha-inducible protein 27. | IFIH1 isoform 1. | 0.598 |
IFI27 | IFIT1 | ENSPTRP00000011379 | ENSPTRP00000090449 | Interferon, alpha-inducible protein 27. | Interferon-induced protein with tetratricopeptide repeats 1. | 0.853 |
IFI27 | IFIT2 | ENSPTRP00000011379 | ENSPTRP00000004778 | Interferon, alpha-inducible protein 27. | Interferon-induced protein with tetratricopeptide repeats 2. | 0.579 |
IFI27 | IFIT3 | ENSPTRP00000011379 | ENSPTRP00000088943 | Interferon, alpha-inducible protein 27. | Interferon-induced protein with tetratricopeptide repeats 3; IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication. Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription. Exihibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B [...] | 0.789 |
IFI27 | OAS1 | ENSPTRP00000011379 | ENSPTRP00000049897 | Interferon, alpha-inducible protein 27. | Oligoadenylate synthetase 1 isoform p46. | 0.869 |
IFI27 | OAS2 | ENSPTRP00000011379 | ENSPTRP00000049895 | Interferon, alpha-inducible protein 27. | 2',5'-oligoadenylate synthetase 2. | 0.696 |
IFI27 | OASL | ENSPTRP00000011379 | ENSPTRP00000009423 | Interferon, alpha-inducible protein 27. | OASL isoform 1. | 0.725 |
IFI27 | RSAD2 | ENSPTRP00000011379 | ENSPTRP00000019995 | Interferon, alpha-inducible protein 27. | RSAD2 isoform 1. | 0.931 |
IFI27 | XAF1 | ENSPTRP00000011379 | ENSPTRP00000014760 | Interferon, alpha-inducible protein 27. | XIAP associated factor 1. | 0.788 |
IFI44 | IFI27 | ENSPTRP00000001546 | ENSPTRP00000011379 | Interferon-induced protein 44; This protein aggregates to form microtubular structures; Belongs to the IFI44 family. | Interferon, alpha-inducible protein 27. | 0.928 |
IFI44 | IFIH1 | ENSPTRP00000001546 | ENSPTRP00000021498 | Interferon-induced protein 44; This protein aggregates to form microtubular structures; Belongs to the IFI44 family. | IFIH1 isoform 1. | 0.921 |
IFI44 | IFIT1 | ENSPTRP00000001546 | ENSPTRP00000090449 | Interferon-induced protein 44; This protein aggregates to form microtubular structures; Belongs to the IFI44 family. | Interferon-induced protein with tetratricopeptide repeats 1. | 0.955 |
IFI44 | IFIT2 | ENSPTRP00000001546 | ENSPTRP00000004778 | Interferon-induced protein 44; This protein aggregates to form microtubular structures; Belongs to the IFI44 family. | Interferon-induced protein with tetratricopeptide repeats 2. | 0.945 |
IFI44 | IFIT3 | ENSPTRP00000001546 | ENSPTRP00000088943 | Interferon-induced protein 44; This protein aggregates to form microtubular structures; Belongs to the IFI44 family. | Interferon-induced protein with tetratricopeptide repeats 3; IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication. Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription. Exihibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B [...] | 0.960 |
IFI44 | OAS1 | ENSPTRP00000001546 | ENSPTRP00000049897 | Interferon-induced protein 44; This protein aggregates to form microtubular structures; Belongs to the IFI44 family. | Oligoadenylate synthetase 1 isoform p46. | 0.939 |
IFI44 | OAS2 | ENSPTRP00000001546 | ENSPTRP00000049895 | Interferon-induced protein 44; This protein aggregates to form microtubular structures; Belongs to the IFI44 family. | 2',5'-oligoadenylate synthetase 2. | 0.923 |
IFI44 | OASL | ENSPTRP00000001546 | ENSPTRP00000009423 | Interferon-induced protein 44; This protein aggregates to form microtubular structures; Belongs to the IFI44 family. | OASL isoform 1. | 0.923 |
IFI44 | RSAD2 | ENSPTRP00000001546 | ENSPTRP00000019995 | Interferon-induced protein 44; This protein aggregates to form microtubular structures; Belongs to the IFI44 family. | RSAD2 isoform 1. | 0.984 |
IFI44 | XAF1 | ENSPTRP00000001546 | ENSPTRP00000014760 | Interferon-induced protein 44; This protein aggregates to form microtubular structures; Belongs to the IFI44 family. | XIAP associated factor 1. | 0.978 |