STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NESNES isoform 1; Belongs to the intermediate filament family. (1620 aa)    
Predicted Functional Partners:
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
    
 
0.831
VIM
Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
    
 
0.824
SOX2
SRY-box transcription factor 2.
    
 
 0.807
NEFM
Neurofilament medium; Belongs to the intermediate filament family.
    
0.768
PAX6
PAX6 isoform 13.
     
 0.767
SOX1
SOX1 isoform 1.
    
 
 0.726
SYNM
SYNM isoform 2; Belongs to the intermediate filament family.
    
0.717
DCX
DCX isoform 5.
      
 0.709
RBFOX3
RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events.
    
 
 0.699
CDK5
Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.
    
 
 0.698
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.