RGS18 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RGS18

Regulator of G protein signaling 18. (235 aa)

Predicted Functional Partners:

GNB5

0.861

GNAQ

0.781

GNA13

0.751

ENSPTRP00000075783

0.693

ENSPTRP00000077377

0.693

GNAO1

0.693

GNA12

0.673

SUCLG2

0.665

B3GALT2

0.663

GNAI2

0.632

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3GALT2	RGS18	ENSPTRP00000064523	ENSPTRP00000002993	Hexosyltransferase.	Regulator of G protein signaling 18.	0.663
ENSPTRP00000075783	GNA12	ENSPTRP00000075783	ENSPTRP00000032219	annotation not available	Guanine nucleotide binding protein (G protein) alpha 12.	0.405
ENSPTRP00000075783	GNA13	ENSPTRP00000075783	ENSPTRP00000016220	annotation not available	Guanine nucleotide binding protein (G protein), alpha 13.	0.539
ENSPTRP00000075783	GNAO1	ENSPTRP00000075783	ENSPTRP00000088044	annotation not available	G protein subunit alpha o1.	0.446
ENSPTRP00000075783	GNB5	ENSPTRP00000075783	ENSPTRP00000012110	annotation not available	GNB5 isoform 1.	0.731
ENSPTRP00000075783	RGS18	ENSPTRP00000075783	ENSPTRP00000002993	annotation not available	Regulator of G protein signaling 18.	0.693
ENSPTRP00000075783	SUCLG2	ENSPTRP00000075783	ENSPTRP00000079150	annotation not available	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.590
ENSPTRP00000077377	GNA12	ENSPTRP00000077377	ENSPTRP00000032219	annotation not available	Guanine nucleotide binding protein (G protein) alpha 12.	0.405
ENSPTRP00000077377	GNA13	ENSPTRP00000077377	ENSPTRP00000016220	annotation not available	Guanine nucleotide binding protein (G protein), alpha 13.	0.539
ENSPTRP00000077377	GNAO1	ENSPTRP00000077377	ENSPTRP00000088044	annotation not available	G protein subunit alpha o1.	0.446
ENSPTRP00000077377	GNB5	ENSPTRP00000077377	ENSPTRP00000012110	annotation not available	GNB5 isoform 1.	0.731
ENSPTRP00000077377	RGS18	ENSPTRP00000077377	ENSPTRP00000002993	annotation not available	Regulator of G protein signaling 18.	0.693
ENSPTRP00000077377	SUCLG2	ENSPTRP00000077377	ENSPTRP00000079150	annotation not available	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.590
GNA12	ENSPTRP00000075783	ENSPTRP00000032219	ENSPTRP00000075783	Guanine nucleotide binding protein (G protein) alpha 12.	annotation not available	0.405
GNA12	ENSPTRP00000077377	ENSPTRP00000032219	ENSPTRP00000077377	Guanine nucleotide binding protein (G protein) alpha 12.	annotation not available	0.405
GNA12	GNA13	ENSPTRP00000032219	ENSPTRP00000016220	Guanine nucleotide binding protein (G protein) alpha 12.	Guanine nucleotide binding protein (G protein), alpha 13.	0.989
GNA12	GNAI2	ENSPTRP00000032219	ENSPTRP00000025802	Guanine nucleotide binding protein (G protein) alpha 12.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	0.595
GNA12	GNAO1	ENSPTRP00000032219	ENSPTRP00000088044	Guanine nucleotide binding protein (G protein) alpha 12.	G protein subunit alpha o1.	0.591
GNA12	GNAQ	ENSPTRP00000032219	ENSPTRP00000049267	Guanine nucleotide binding protein (G protein) alpha 12.	Guanine nucleotide binding protein (G protein), q polypeptide.	0.759
GNA12	GNB5	ENSPTRP00000032219	ENSPTRP00000012110	Guanine nucleotide binding protein (G protein) alpha 12.	GNB5 isoform 1.	0.888