STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAX2Uncharacterized protein; Paired box 2 (396 aa)    
Predicted Functional Partners:
WT1
Wilms tumor 1
    
 
 0.894
ETS1
Uncharacterized protein; V-ets avian erythroblastosis virus E26 oncogene homolog 1
    
 
 0.841
SHH
Uncharacterized protein
    
 
 0.757
EYA1
Eyes absent homolog; EYA transcriptional coactivator and phosphatase 1; Belongs to the HAD-like hydrolase superfamily. EYA family
    
 
 0.757
LHX1
LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity)
   
 
 0.753
FGF8
Uncharacterized protein; Fibroblast growth factor 8 (androgen-induced); Belongs to the heparin-binding growth factors family
    
 
 0.718
GBX2
Uncharacterized protein
    
 
 0.711
ETS2
Uncharacterized protein
    
 
 0.702
WNT4
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors
   
 
 0.696
PAXIP1
Uncharacterized protein; PAX interacting (with transcription-activation domain) protein 1
    
 
 0.664
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, Pan troglodytes, chimpanzee
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