node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADM | GNAS | ENSPTRP00000005860 | ENSPTRP00000059419 | Adrenomedullin. | GNAS isoform 19. | 0.812 |
ADM | GNB1 | ENSPTRP00000005860 | ENSPTRP00000067330 | Adrenomedullin. | Guanine nucleotide binding protein (G protein), beta polypeptide 1. | 0.757 |
ADM | GNG2 | ENSPTRP00000005860 | ENSPTRP00000065345 | Adrenomedullin. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.757 |
ADM | MRGPRX2 | ENSPTRP00000005860 | ENSPTRP00000005975 | Adrenomedullin. | Mas-related G-protein coupled receptor member X2; Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction; Belongs to the G-protein coupl [...] | 0.865 |
CAMP | MRGPRX2 | ENSPTRP00000025671 | ENSPTRP00000005975 | Cathelicidin antimicrobial peptide; Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity; Belongs to the cathelicidin family. | Mas-related G-protein coupled receptor member X2; Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction; Belongs to the G-protein coupl [...] | 0.793 |
CORT | GNAS | ENSPTRP00000090682 | ENSPTRP00000059419 | CENPS isoform 4. | GNAS isoform 19. | 0.527 |
CORT | GNG2 | ENSPTRP00000090682 | ENSPTRP00000065345 | CENPS isoform 4. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.496 |
CORT | MRGPRX2 | ENSPTRP00000090682 | ENSPTRP00000005975 | CENPS isoform 4. | Mas-related G-protein coupled receptor member X2; Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction; Belongs to the G-protein coupl [...] | 0.813 |
CORT | SST | ENSPTRP00000090682 | ENSPTRP00000067169 | CENPS isoform 4. | SST isoform 1. | 0.979 |
GNAI1 | GNAS | ENSPTRP00000071974 | ENSPTRP00000059419 | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. | GNAS isoform 19. | 0.768 |
GNAI1 | GNB1 | ENSPTRP00000071974 | ENSPTRP00000067330 | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. | Guanine nucleotide binding protein (G protein), beta polypeptide 1. | 0.998 |
GNAI1 | GNG2 | ENSPTRP00000071974 | ENSPTRP00000065345 | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.995 |
GNAI1 | MRGPRX2 | ENSPTRP00000071974 | ENSPTRP00000005975 | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. | Mas-related G-protein coupled receptor member X2; Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction; Belongs to the G-protein coupl [...] | 0.826 |
GNAI1 | SST | ENSPTRP00000071974 | ENSPTRP00000067169 | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. | SST isoform 1. | 0.814 |
GNAS | ADM | ENSPTRP00000059419 | ENSPTRP00000005860 | GNAS isoform 19. | Adrenomedullin. | 0.812 |
GNAS | CORT | ENSPTRP00000059419 | ENSPTRP00000090682 | GNAS isoform 19. | CENPS isoform 4. | 0.527 |
GNAS | GNAI1 | ENSPTRP00000059419 | ENSPTRP00000071974 | GNAS isoform 19. | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. | 0.768 |
GNAS | GNB1 | ENSPTRP00000059419 | ENSPTRP00000067330 | GNAS isoform 19. | Guanine nucleotide binding protein (G protein), beta polypeptide 1. | 0.998 |
GNAS | GNG2 | ENSPTRP00000059419 | ENSPTRP00000065345 | GNAS isoform 19. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.987 |
GNAS | MRGPRX2 | ENSPTRP00000059419 | ENSPTRP00000005975 | GNAS isoform 19. | Mas-related G-protein coupled receptor member X2; Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction; Belongs to the G-protein coupl [...] | 0.826 |