STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
U2AF1-2U2 small nuclear RNA auxiliary factor 1. (241 aa)    
Predicted Functional Partners:
U2AF2
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
   
 0.979
SRSF2
Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5 [...]
   
 0.866
SRSF1
Serine and arginine rich splicing factor 1.
   
 0.864
SNRPB2
Small nuclear ribonucleoprotein polypeptide B2.
   
 
 0.740
SF3A2
Splicing factor 3a, subunit 2, 66kDa.
   
 
 0.682
U2AF1L4
U2 small nuclear RNA auxiliary factor 1.
  
 
 
0.677
SRSF7
Serine and arginine rich splicing factor 7.
   
 0.663
CK820_G0038484
ZRSR1 isoform 1.
   
 
0.658
ZRSR2
Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2.
   
 
0.658
ENSPTRP00000066498
annotation not available
   
 
0.658
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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