STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL11Kelch like family member 11. (708 aa)    
Predicted Functional Partners:
CUL3
CUL3 isoform 2; Belongs to the cullin family.
    
 0.987
KBTBD13
Kelch repeat and BTB domain containing 13.
     
 0.706
NAE1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
     
 0.694
CUL1
CUL1 isoform 1; Belongs to the cullin family.
    
 0.663
ENSPTRP00000064916
annotation not available
    
 0.663
CUL1-2
Cullin 1.
    
 0.663
NEDD8
Ubiquitin-like protein Nedd8.
     
 0.577
KLHL26
Kelch like family member 26.
    
0.562
RBX1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.560
KLHL20
Kelch like family member 20.
    
0.553
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.