STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXN2FOXN2 isoform 2. (431 aa)    
Predicted Functional Partners:
TNFSF12
Tumor necrosis factor (Ligand) superfamily, member 12; Belongs to the tumor necrosis factor family.
      
 0.581
ETS1
ETS proto-oncogene 1, transcription factor.
    
 
 0.567
POLR3A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.510
SHPRH
SNF2 histone linker PHD RING helicase.
    
 0.505
HLTF
Helicase-like transcription factor.
   
 0.504
FBXW11
F-box and WD repeat domain containing 11.
   
 
 0.484
DHRS4
Dehydrogenase/reductase (SDR family) member 4.
    
 
 0.473
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
   
 
 0.464
FBXO11
F-box protein 11.
   
 
 0.431
UBE2V2
Ubiquitin-conjugating enzyme E2 variant 2.
     
 0.410
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.