STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXN2Forkhead box N2; Uncharacterized protein (431 aa)    
Predicted Functional Partners:
POLR3A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
    
 
 0.781
SFTA3
Surfactant associated 3
      
 0.708
SHPRH
Uncharacterized protein; SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
   
 
 0.699
HOXC13
Uncharacterized protein; Homeobox C13
    
 
 0.693
PIP4K2A
Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
      
 0.584
HLTF
Helicase-like transcription factor; Uncharacterized protein
   
 
 0.573
MBTD1
Mbt domain containing 1
    
 
 0.571
KDM3A
Lysine (K)-specific demethylase 3A; Uncharacterized protein
      
 0.563
MSX2
Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter (By similarity)
    
 
 0.561
ETS1
Uncharacterized protein; V-ets avian erythroblastosis virus E26 oncogene homolog 1
    
 
 0.538
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, Pan troglodytes, chimpanzee
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