STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ST3GAL5Lactosylceramide alpha-2,3-sialyltransferase; Catalyzes the formation of ganglioside GM3 (alpha-N- acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D-glucosylceramide). (437 aa)    
Predicted Functional Partners:
ST8SIA1
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid.
     
 0.963
HEXB
Beta-hexosaminidase.
     
 0.915
CELF6-2
CUGBP Elav-like family member 6 isoform X1.
     
 0.910
GLB1
Beta-galactosidase.
   
 
 0.847
VSIG10
V-set and immunoglobulin domain containing 10.
      
 0.689
DYNLT1
Dynein, light chain, Tctex-type 1.
      
 0.661
SLC35A1
Solute carrier family 35 (CMP-sialic acid transporter), member A1.
      
 0.606
NANS
N-acetylneuraminate synthase.
      
 0.605
TOR1B
Torsin.
      
 0.577
TOR1A
Torsin.
      
 0.576
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.