STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CSF2RBColony stimulating factor 2 receptor, beta, low-affinity (Granulocyte-macrophage). (904 aa)    
Predicted Functional Partners:
CSF2
Colony stimulating factor 2.
    
 0.999
CSF2RA
CSF2RA isoform 11.
   
 0.999
IL3
Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
    
 0.998
JAK2
Tyrosine-protein kinase.
   
 0.989
IL5
Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.
    
 0.980
CK820_G0056611
IL3RA isoform 1.
   
 0.974
JAK1
Tyrosine-protein kinase.
   
 0.973
IL5RA
Interleukin 5 receptor subunit alpha.
    
 0.968
NRAS
Neuroblastoma RAS viral (V-ras) oncogene homolog.
   
 
  0.920
HRAS
V-Ha-ras Harvey rat sarcoma viral oncogene homolog.
   
 
  0.920
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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