STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF3Rho guanine nucleotide exchange factor (GEF) 3. (558 aa)    
Predicted Functional Partners:
RHOB
Ras homolog gene family, member B.
    
 0.846
RHOC
Rho-related GTP-binding protein RhoC isoform X1.
    
 0.813
RHOA
Ras homolog family member A.
    
 0.761
RHOG
Ras homolog gene family, member G (Rho G).
   
 0.657
CDC42
Cell division cycle 42 (GTP binding protein, 25kDa).
   
 0.655
PRKAR2B
Protein kinase, cAMP-dependent, regulatory, type II, beta.
      
 0.627
WDR66
WD repeat domain 66.
    
 
 0.626
RND1
RND1 isoform 1.
    
 0.603
RHOF
Ras homolog family member F, filopodia associated.
    
 0.603
RND3
Rho family GTPase 3.
    
 0.603
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.