node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASPM | CENPJ | ENSPTRP00000051373 | ENSPTRP00000009739 | Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). | Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...] | 0.879 |
ASPM | CEP135 | ENSPTRP00000051373 | ENSPTRP00000027649 | Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). | Centrosomal protein 135kDa. | 0.604 |
ASPM | CEP152 | ENSPTRP00000051373 | ENSPTRP00000082235 | Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). | Centrosomal protein 152kDa. | 0.818 |
ASPM | CEP63 | ENSPTRP00000051373 | ENSPTRP00000026578 | Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). | Centrosomal protein 63kDa. | 0.666 |
ASPM | PLK1 | ENSPTRP00000051373 | ENSPTRP00000093799 | Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). | Serine/threonine-protein kinase PLK. | 0.478 |
ASPM | PLK4 | ENSPTRP00000051373 | ENSPTRP00000028220 | Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). | Polo-like kinase 4. | 0.699 |
ASPM | STIL | ENSPTRP00000051373 | ENSPTRP00000084476 | Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). | STIL centriolar assembly protein. | 0.911 |
ASPM | WDR62 | ENSPTRP00000051373 | ENSPTRP00000018646 | Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). | WDR62 isoform 2. | 0.885 |
CCDC14 | CEP135 | ENSPTRP00000070334 | ENSPTRP00000027649 | CCDC14 isoform 12. | Centrosomal protein 135kDa. | 0.548 |
CCDC14 | CEP63 | ENSPTRP00000070334 | ENSPTRP00000026578 | CCDC14 isoform 12. | Centrosomal protein 63kDa. | 0.877 |
CENPJ | ASPM | ENSPTRP00000009739 | ENSPTRP00000051373 | Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...] | Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). | 0.879 |
CENPJ | CEP135 | ENSPTRP00000009739 | ENSPTRP00000027649 | Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...] | Centrosomal protein 135kDa. | 0.932 |
CENPJ | CEP152 | ENSPTRP00000009739 | ENSPTRP00000082235 | Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...] | Centrosomal protein 152kDa. | 0.961 |
CENPJ | CEP63 | ENSPTRP00000009739 | ENSPTRP00000026578 | Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...] | Centrosomal protein 63kDa. | 0.742 |
CENPJ | PLK1 | ENSPTRP00000009739 | ENSPTRP00000093799 | Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...] | Serine/threonine-protein kinase PLK. | 0.938 |
CENPJ | PLK4 | ENSPTRP00000009739 | ENSPTRP00000028220 | Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...] | Polo-like kinase 4. | 0.922 |
CENPJ | STIL | ENSPTRP00000009739 | ENSPTRP00000084476 | Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...] | STIL centriolar assembly protein. | 0.960 |
CENPJ | WDR62 | ENSPTRP00000009739 | ENSPTRP00000018646 | Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...] | WDR62 isoform 2. | 0.798 |
CEP135 | ASPM | ENSPTRP00000027649 | ENSPTRP00000051373 | Centrosomal protein 135kDa. | Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). | 0.604 |
CEP135 | CCDC14 | ENSPTRP00000027649 | ENSPTRP00000070334 | Centrosomal protein 135kDa. | CCDC14 isoform 12. | 0.548 |