STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCN1HCN1 isoform 1. (886 aa)    
Predicted Functional Partners:
HCN3
Hyperpolarization activated cyclic nucleotide gated potassium channel 3.
  
 
0.938
HCN4
Hyperpolarization activated cyclic nucleotide gated potassium channel 4.
  
 
0.814
HCN2
Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2.
  
 
0.743
CK820_G0013720
HCN2 isoform 1.
  
 
0.742
PEX5L
Peroxisomal biogenesis factor 5 like.
   
 
 0.580
GNAT3
G protein subunit alpha transducin 3.
      
 0.493
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.