TFEB protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TFEB

Transcription factor EB. (490 aa)

Predicted Functional Partners:

MITF

0.955

MTOR

0.910

RRAGC

0.893

RRAGA

0.892

RPTOR

0.875

YWHAG

0.829

TFE3

0.797

MLST8

0.768

LAMTOR1

0.766

LAMTOR4

0.735

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LAMTOR1	LAMTOR4	ENSPTRP00000006924	ENSPTRP00000060571	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	0.999
LAMTOR1	MLST8	ENSPTRP00000006924	ENSPTRP00000070104	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	MLST8 isoform 3.	0.932
LAMTOR1	MTOR	ENSPTRP00000006924	ENSPTRP00000000280	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.944
LAMTOR1	RPTOR	ENSPTRP00000006924	ENSPTRP00000016590	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	Regulatory associated protein of MTOR, complex 1.	0.998
LAMTOR1	RRAGA	ENSPTRP00000006924	ENSPTRP00000035579	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	Ras-related GTP binding A.	0.999
LAMTOR1	RRAGC	ENSPTRP00000006924	ENSPTRP00000000985	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	Ras related GTP binding C.	0.999
LAMTOR1	TFEB	ENSPTRP00000006924	ENSPTRP00000074118	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	Transcription factor EB.	0.766
LAMTOR4	LAMTOR1	ENSPTRP00000060571	ENSPTRP00000006924	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	0.999
LAMTOR4	MLST8	ENSPTRP00000060571	ENSPTRP00000070104	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	MLST8 isoform 3.	0.922
LAMTOR4	MTOR	ENSPTRP00000060571	ENSPTRP00000000280	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.913
LAMTOR4	RPTOR	ENSPTRP00000060571	ENSPTRP00000016590	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	Regulatory associated protein of MTOR, complex 1.	0.998
LAMTOR4	RRAGA	ENSPTRP00000060571	ENSPTRP00000035579	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	Ras-related GTP binding A.	0.999
LAMTOR4	RRAGC	ENSPTRP00000060571	ENSPTRP00000000985	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	Ras related GTP binding C.	0.999
LAMTOR4	TFEB	ENSPTRP00000060571	ENSPTRP00000074118	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	Transcription factor EB.	0.735
MITF	MTOR	ENSPTRP00000085305	ENSPTRP00000000280	MITF isoform 1.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.490
MITF	RPTOR	ENSPTRP00000085305	ENSPTRP00000016590	MITF isoform 1.	Regulatory associated protein of MTOR, complex 1.	0.429
MITF	TFE3	ENSPTRP00000085305	ENSPTRP00000037562	MITF isoform 1.	Transcription factor binding to IGHM enhancer 3.	0.935
MITF	TFEB	ENSPTRP00000085305	ENSPTRP00000074118	MITF isoform 1.	Transcription factor EB.	0.955
MLST8	LAMTOR1	ENSPTRP00000070104	ENSPTRP00000006924	MLST8 isoform 3.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	0.932
MLST8	LAMTOR4	ENSPTRP00000070104	ENSPTRP00000060571	MLST8 isoform 3.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	0.922