STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FEZF1FEZ family zinc finger 1. (475 aa)    
Predicted Functional Partners:
LHX5
LHX5 isoform 2.
   
 
 0.742
ZNF804A
Zinc finger protein 804A.
   
 
 0.553
ZNF385B
Zinc finger protein 385B.
      
 0.537
CNP
2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.
    
 
 0.496
SSTR2
Somatostatin receptor type 2; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.486
TSHZ3
Teashirt zinc finger homeobox 3.
      
 0.482
PROKR2
Prokineticin receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.459
HS6ST1
Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
      
 0.457
LHX9
LHX9 isoform 2.
  
 
 0.455
KRAS
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
    
 0.450
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.