STRINGSTRING
IL1RAPL1 protein (Pan troglodytes) - STRING interaction network
"IL1RAPL1" - Interleukin-1 receptor accessory protein-like 1 in Pan troglodytes
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL1RAPL1Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity) (437 aa)    
Predicted Functional Partners:
NCS1
Neuronal calcium sensor 1 (140 aa)
     
 
  0.908
PTPRD
Protein tyrosine phosphatase, receptor type, D (1911 aa)
     
 
  0.787
SHANK1
Uncharacterized protein; SH3 and multiple ankyrin repeat domains 1 (1360 aa)
     
 
  0.769
SHANK2
SH3 and multiple ankyrin repeat domains 2 (1849 aa)
     
 
  0.737
MAGEB10
MAGE family member B10; Melanoma antigen family B, 10 (347 aa)
           
  0.729
SHANK3
SH3 and multiple ankyrin repeat domains 3 (1557 aa)
     
 
  0.722
TBC1D8
Uncharacterized protein (1155 aa)
           
  0.717
RNF149
Ring finger protein 149; Uncharacterized protein (400 aa)
           
  0.717
DLG4
Uncharacterized protein; Discs, large homolog 4 (Drosophila); Belongs to the MAGUK family (767 aa)
     
 
  0.709
BCOR
BCL6 corepressor (1645 aa)
           
  0.654
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, Pan troglodytes, chimpanzee
Server load: low (11%) [HD]