STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCRBCR activator of RhoGEF and GTPase. (1271 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2.
    
 0.990
ABL1
Tyrosine-protein kinase.
    
 0.978
CBL
Cas-Br-M (Murine) ecotropic retroviral transforming sequence.
    
  0.948
CRKL
V-crk sarcoma virus CT10 oncogene homolog (Avian)-like.
    
 0.945
CRK
V-crk sarcoma virus CT10 oncogene homolog (Avian).
    
 0.912
SHC1
SHC (Src homology 2 domain containing) transforming protein 1.
    
 0.904
SHC3
SHC3 isoform 2.
    
 0.901
SHC4
SHC adaptor protein 4.
    
  0.900
CK820_G0012168
ABL1 isoform 3.
    
 0.790
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
    
   0.695
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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