STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCC8ABCC8 isoform 2. (1582 aa)    
Predicted Functional Partners:
KCNJ11
Potassium voltage-gated channel subfamily J member 11.
 
 
 0.999
RAPGEF4
RAPGEF4 isoform 2.
    
 0.987
KCNJ8
Potassium inwardly-rectifying channel, subfamily J, member 8.
   
 0.982
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
 
 
 0.955
PRKACG
Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.
 
 
 0.954
PRKACA
PRKACA isoform 7; Belongs to the protein kinase superfamily.
 
 
 0.953
GCK
Phosphotransferase.
   
 
 0.717
RAPGEF3
Rap guanine nucleotide exchange factor 3.
    
 0.692
HNF1A
HNF1 homeobox A.
   
  
 0.684
TRPM4
Transient receptor potential cation channel, subfamily M, member 4.
      
 0.672
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.