STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGI3Leucine-rich repeat LGI family member 3; May participate in the regulation of neuronal exocytosis. (548 aa)    
Predicted Functional Partners:
ADAM23
ADAM metallopeptidase domain 23.
   
 
 0.787
ADAM22
ADAM metallopeptidase domain 22.
   
 
 0.715
ADAM22-2
ADAM22 isoform 3.
   
 
 0.715
ADAM28
ADAM28 isoform 1.
     
 0.585
SFTPC
Surfactant protein C.
   
  
 0.577
ADAM11
ADAM metallopeptidase domain 11.
   
 
 0.528
PHYHIP
Phytanoyl-CoA 2-hydroxylase interacting protein.
  
  
 0.492
MTUS1
Microtubule associated scaffold protein 1.
    
 
 0.434
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.