node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BMP4 | LEF1 | ENSPTRP00000010780 | ENSPTRP00000079959 | Bone morphogenetic protein 4. | Lymphoid enhancer binding factor 1. | 0.626 |
BMP4 | MSX1 | ENSPTRP00000010780 | ENSPTRP00000055966 | Bone morphogenetic protein 4. | Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). | 0.682 |
BMP4 | MSX2 | ENSPTRP00000010780 | ENSPTRP00000029971 | Bone morphogenetic protein 4. | Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter (By similarity); Belongs to the Msh homeobox family. | 0.614 |
BMP4 | OSR2 | ENSPTRP00000010780 | ENSPTRP00000093845 | Bone morphogenetic protein 4. | Protein odd-skipped-related 2 isoform X4. | 0.400 |
BMP4 | PAX9 | ENSPTRP00000010780 | ENSPTRP00000010655 | Bone morphogenetic protein 4. | Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. | 0.576 |
BMP4-2 | LEF1 | ENSPTRP00000080656 | ENSPTRP00000079959 | Bone morphogenetic protein 4. | Lymphoid enhancer binding factor 1. | 0.626 |
BMP4-2 | MSX1 | ENSPTRP00000080656 | ENSPTRP00000055966 | Bone morphogenetic protein 4. | Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). | 0.682 |
BMP4-2 | MSX2 | ENSPTRP00000080656 | ENSPTRP00000029971 | Bone morphogenetic protein 4. | Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter (By similarity); Belongs to the Msh homeobox family. | 0.614 |
BMP4-2 | OSR2 | ENSPTRP00000080656 | ENSPTRP00000093845 | Bone morphogenetic protein 4. | Protein odd-skipped-related 2 isoform X4. | 0.400 |
BMP4-2 | PAX9 | ENSPTRP00000080656 | ENSPTRP00000010655 | Bone morphogenetic protein 4. | Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. | 0.576 |
HIST1H1B | MSX1 | ENSPTRP00000030452 | ENSPTRP00000055966 | HIST1H1B isoform 1. | Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). | 0.803 |
LEF1 | BMP4 | ENSPTRP00000079959 | ENSPTRP00000010780 | Lymphoid enhancer binding factor 1. | Bone morphogenetic protein 4. | 0.626 |
LEF1 | BMP4-2 | ENSPTRP00000079959 | ENSPTRP00000080656 | Lymphoid enhancer binding factor 1. | Bone morphogenetic protein 4. | 0.626 |
LEF1 | LHX8 | ENSPTRP00000079959 | ENSPTRP00000072266 | Lymphoid enhancer binding factor 1. | LHX8 isoform 2. | 0.408 |
LEF1 | MSX1 | ENSPTRP00000079959 | ENSPTRP00000055966 | Lymphoid enhancer binding factor 1. | Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). | 0.676 |
LEF1 | MSX2 | ENSPTRP00000079959 | ENSPTRP00000029971 | Lymphoid enhancer binding factor 1. | Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter (By similarity); Belongs to the Msh homeobox family. | 0.433 |
LEF1 | PAX9 | ENSPTRP00000079959 | ENSPTRP00000010655 | Lymphoid enhancer binding factor 1. | Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. | 0.494 |
LHX8 | LEF1 | ENSPTRP00000072266 | ENSPTRP00000079959 | LHX8 isoform 2. | Lymphoid enhancer binding factor 1. | 0.408 |
LHX8 | MSX1 | ENSPTRP00000072266 | ENSPTRP00000055966 | LHX8 isoform 2. | Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). | 0.678 |
LHX8 | PAX9 | ENSPTRP00000072266 | ENSPTRP00000010655 | LHX8 isoform 2. | Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. | 0.657 |