STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBE2HUbiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)    
Predicted Functional Partners:
UBA1
UBA1 isoform 3; Belongs to the ubiquitin-activating E1 family.
    
 0.901
UBA3
Ubiquitin-like modifier-activating enzyme 3.
    
 0.833
UBE2W
T0076549 isoform 1.
   
 0.784
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
    
 0.747
UBE2K
Ubiquitin-conjugating enzyme E2-25 kDa; Belongs to the ubiquitin-conjugating enzyme family.
   
0.745
UBA7
Ubiquitin-like modifier-activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
    
 0.736
UBA6
Ubiquitin-like modifier-activating enzyme 6.
    
 0.730
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.727
BIRC6
BIRC6 isoform 5.
   
 0.722
UBA5
Ubiquitin-like modifier-activating enzyme 5.
    
 0.719
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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