STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THEM4Thioesterase superfamily member 4. (240 aa)    
Predicted Functional Partners:
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.968
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.949
ACOT7
Acyl-CoA thioesterase 7.
     
 0.933
THEM5
Thioesterase superfamily member 5.
  
 
 
0.928
ACOT2
ACOT2 isoform 1.
     
 0.915
ACOT4
ACOT4 isoform 1.
     
 0.915
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.896
PDPK1
PDPK1 isoform 1.
     
 0.545
ACOT9
Acyl-CoA thioesterase 9.
     
 0.545
ENOPH1
Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
    
 
 0.465
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.