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CELF2 protein (Pongo abelii) - STRING interaction network
"CELF2" - CUGBP Elav-like family member 2 in Pongo abelii
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CELF2CUGBP Elav-like family member 2; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in embryonic, but not adult, skeletal muscle. Activates TNNT2 exon 5 inclusion by antagonizing the repressive effect of PTB. Acts as both an activator and repressor of a pair of coregulated exons- promotes [...] (514 aa)    
Predicted Functional Partners:
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta (269 aa)
     
   
  0.761
MBNL3
Muscleblind-like splicing regulator 3 (354 aa)
     
 
  0.741
ENSPPYG00000017536
Uncharacterized protein (279 aa)
     
 
  0.698
HNRNPC
Heterogeneous nuclear ribonucleoprotein C; Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3’-UTR or 5’-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre- mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named ’m(6)A-switch’, facili [...] (306 aa)
     
 
  0.698
FAM150B
ALK and LTK ligand 2; Family with sequence similarity 150, member B (152 aa)
           
  0.661
PKIA
Protein kinase (cAMP-dependent, catalytic) inhibitor alpha; Belongs to the PKI family (76 aa)
     
   
  0.660
MBNL1
Muscleblind-like splicing regulator 1 (381 aa)
     
 
  0.656
MBNL2
Muscleblind-like protein 2; Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. RNA-binding protein that binds to 5’ACACCC-3’ core sequence, termed zipcode, within the 3’UTR of ITGA3. Binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. Seems to regulate expr [...] (385 aa)
     
 
  0.654
RALY
RALY heterogeneous nuclear ribonucleoprotein (303 aa)
     
 
  0.650
RBM24
RNA binding motif protein 24 (236 aa)
     
 
  0.602
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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