STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFXN3Sideroflexin-3; Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. Belongs to the sideroflexin family. (321 aa)    
Predicted Functional Partners:
RUNX1T1
RUNX1 partner transcriptional co-repressor 1.
   
    0.497
P2RX1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
   
  
 0.429
CR201_G0049662
CREG2 isoform 1.
      
 0.422
LEMD3
LEMD3 isoform 1.
      
 0.420
WIPF1
WAS/WASL interacting protein family member 1.
      
 0.420
SREK1IP1
SREK1 interacting protein 1.
      
 0.420
ZNF572
ZNF572 isoform 1.
      
 0.420
SH3TC2
SH3TC2 isoform 8.
      
 0.418
CBFA2T3
CBFA2T3 isoform 1.
   
    0.400
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (26%) [HD]