LTBP3 protein (Pongo abelii) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

LTBP3

LTBP3 isoform 3. (1245 aa)

Predicted Functional Partners:

TGFB1

0.940

TGFB2

0.918

TGFB3

0.853

MSTN

0.691

FBN1

0.583

ITGB6

0.577

WNT10A

0.577

FBLN5

0.563

PAX9

0.543

LTBP4

0.512

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FBLN5	FBN1	ENSPPYP00000006903	ENSPPYP00000007315	Fibulin-5; Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN. Belongs to the fibulin family.	FBN1 isoform 1.	0.749
FBLN5	LTBP3	ENSPPYP00000006903	ENSPPYP00000003545	Fibulin-5; Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN. Belongs to the fibulin family.	LTBP3 isoform 3.	0.563
FBLN5	LTBP4	ENSPPYP00000006903	ENSPPYP00000011191	Fibulin-5; Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN. Belongs to the fibulin family.	LTBP4 isoform 2.	0.429
FBN1	FBLN5	ENSPPYP00000007315	ENSPPYP00000006903	FBN1 isoform 1.	Fibulin-5; Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN. Belongs to the fibulin family.	0.749
FBN1	ITGB6	ENSPPYP00000007315	ENSPPYP00000014370	FBN1 isoform 1.	Integrin beta; Belongs to the integrin beta chain family.	0.599
FBN1	LTBP3	ENSPPYP00000007315	ENSPPYP00000003545	FBN1 isoform 1.	LTBP3 isoform 3.	0.583
FBN1	LTBP4	ENSPPYP00000007315	ENSPPYP00000011191	FBN1 isoform 1.	LTBP4 isoform 2.	0.450
FBN1	MSTN	ENSPPYP00000007315	ENSPPYP00000014545	FBN1 isoform 1.	MSTN isoform 1.	0.439
FBN1	TGFB1	ENSPPYP00000007315	ENSPPYP00000011208	FBN1 isoform 1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.771
FBN1	TGFB2	ENSPPYP00000007315	ENSPPYP00000000219	FBN1 isoform 1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.664
FBN1	TGFB3	ENSPPYP00000007315	ENSPPYP00000006835	FBN1 isoform 1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.581
ITGB6	FBN1	ENSPPYP00000014370	ENSPPYP00000007315	Integrin beta; Belongs to the integrin beta chain family.	FBN1 isoform 1.	0.599
ITGB6	LTBP3	ENSPPYP00000014370	ENSPPYP00000003545	Integrin beta; Belongs to the integrin beta chain family.	LTBP3 isoform 3.	0.577
ITGB6	LTBP4	ENSPPYP00000014370	ENSPPYP00000011191	Integrin beta; Belongs to the integrin beta chain family.	LTBP4 isoform 2.	0.566
ITGB6	TGFB1	ENSPPYP00000014370	ENSPPYP00000011208	Integrin beta; Belongs to the integrin beta chain family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.972
ITGB6	TGFB2	ENSPPYP00000014370	ENSPPYP00000000219	Integrin beta; Belongs to the integrin beta chain family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.768
ITGB6	TGFB3	ENSPPYP00000014370	ENSPPYP00000006835	Integrin beta; Belongs to the integrin beta chain family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.733
LTBP3	FBLN5	ENSPPYP00000003545	ENSPPYP00000006903	LTBP3 isoform 3.	Fibulin-5; Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN. Belongs to the fibulin family.	0.563
LTBP3	FBN1	ENSPPYP00000003545	ENSPPYP00000007315	LTBP3 isoform 3.	FBN1 isoform 1.	0.583
LTBP3	ITGB6	ENSPPYP00000003545	ENSPPYP00000014370	LTBP3 isoform 3.	Integrin beta; Belongs to the integrin beta chain family.	0.577