node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTA1 | CAP1 | ENSPPYP00000000129 | ENSPPYP00000001729 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. | 0.901 |
ACTA1 | CAPZB | ENSPPYP00000000129 | ENSPPYP00000002072 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). | 0.929 |
ACTA1 | MYO1C | ENSPPYP00000000129 | ENSPPYP00000008755 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | MYO1C isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.440 |
ACTA1 | TWF1 | ENSPPYP00000000129 | ENSPPYP00000005055 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Twinfilin-1; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). Belongs to the actin-binding proteins ADF family. Twinfilin subfamily. | 0.904 |
CAP1 | ACTA1 | ENSPPYP00000001729 | ENSPPYP00000000129 | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | 0.901 |
CAP1 | CAPZB | ENSPPYP00000001729 | ENSPPYP00000002072 | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). | 0.504 |
CAP1 | GRXCR1 | ENSPPYP00000001729 | ENSPPYP00000016422 | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. | GRXCR1 isoform 1. | 0.637 |
CAP1 | GRXCR2 | ENSPPYP00000001729 | ENSPPYP00000017792 | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. | Glutaredoxin and cysteine rich domain containing 2. | 0.465 |
CAP1 | TWF1 | ENSPPYP00000001729 | ENSPPYP00000005055 | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. | Twinfilin-1; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). Belongs to the actin-binding proteins ADF family. Twinfilin subfamily. | 0.896 |
CAPZB | ACTA1 | ENSPPYP00000002072 | ENSPPYP00000000129 | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | 0.929 |
CAPZB | CAP1 | ENSPPYP00000002072 | ENSPPYP00000001729 | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. | 0.504 |
CAPZB | PLS1 | ENSPPYP00000002072 | ENSPPYP00000015854 | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). | PLS1 isoform 1. | 0.680 |
CAPZB | TWF1 | ENSPPYP00000002072 | ENSPPYP00000005055 | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). | Twinfilin-1; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). Belongs to the actin-binding proteins ADF family. Twinfilin subfamily. | 0.942 |
CR201_G0023224 | GRXCR1 | ENSPPYP00000004234 | ENSPPYP00000016422 | MYO7A isoform 2. | GRXCR1 isoform 1. | 0.921 |
CR201_G0023224 | GRXCR2 | ENSPPYP00000004234 | ENSPPYP00000017792 | MYO7A isoform 2. | Glutaredoxin and cysteine rich domain containing 2. | 0.905 |
CR201_G0023224 | MYO1C | ENSPPYP00000004234 | ENSPPYP00000008755 | MYO7A isoform 2. | MYO1C isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.894 |
CR201_G0023224 | PLS1 | ENSPPYP00000004234 | ENSPPYP00000015854 | MYO7A isoform 2. | PLS1 isoform 1. | 0.899 |
CR201_G0023224 | RDX | ENSPPYP00000004234 | ENSPPYP00000004412 | MYO7A isoform 2. | RDX isoform 3. | 0.933 |
CR201_G0023224 | TPRN | ENSPPYP00000004234 | ENSPPYP00000022217 | MYO7A isoform 2. | TPRN isoform 2. | 0.921 |
CR201_G0023224 | TWF1 | ENSPPYP00000004234 | ENSPPYP00000005055 | MYO7A isoform 2. | Twinfilin-1; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). Belongs to the actin-binding proteins ADF family. Twinfilin subfamily. | 0.907 |