STRINGSTRING
CRADD protein (Pongo abelii) - STRING interaction network
"CRADD" - Death domain-containing protein CRADD in Pongo abelii
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRADDDeath domain-containing protein CRADD ; Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex (By similarity) (199 aa)    
Predicted Functional Partners:
CASP2
Caspase 2, apoptosis-related cysteine peptidase (452 aa)
       
  0.861
PIDD
P53-induced death domain protein (825 aa)
       
  0.815
FADD
Fas (TNFRSF6)-associated via death domain (208 aa)
         
  0.468
ANKRD44
Ankyrin repeat domain 44 (969 aa)
       
  0.456
TRADD
TNFRSF1A-associated via death domain (234 aa)
     
 
  0.448
ENSPPYG00000018949
Uncharacterized protein (229 aa)
       
  0.446
ANK1
Ankyrin 1, erythrocytic (1695 aa)
       
  0.446
TNKS
Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (1327 aa)
       
  0.446
ANKRD61
Ankyrin repeat domain 61 (417 aa)
       
  0.446
HACE1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (909 aa)
       
  0.446
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Ponginae, Pongo, Pongo abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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