STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FARP1FERM, ARHGEF and pleckstrin domain-containing protein 1; Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity). (1045 aa)    
Predicted Functional Partners:
NDUFA1
NDUFA1 isoform 1.
      
 0.812
DCAF12L1
DDB1 and CUL4 associated factor 12 like 1.
      
 0.790
DCAF12
DDB1 and CUL4 associated factor 12.
      
 0.768
CDC42
Cell division cycle 42.
    
 0.615
PLXNA4
PLXNA4 isoform 2.
     
 0.604
SEMA6A
SEMA6A isoform 1; Belongs to the semaphorin family.
     
 0.546
PLXND1
PLXND1 isoform 1.
     
 0.521
NRP1
Neuropilin; Belongs to the neuropilin family.
     
 0.513
PLEK2
PLEK2 isoform 1.
      
 0.503
MST1R
MST1R isoform 1.
    
 0.503
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: medium (48%) [HD]