STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHRS4Dehydrogenase/reductase SDR family member 4; Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha- dicarbonyl compounds with aromatic rings, such as pyrimidine-4- aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4- hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity). (278 aa)    
Predicted Functional Partners:
ALDH1A1
ALDH1A1 isoform 5; Belongs to the aldehyde dehydrogenase family.
  
 0.943
DHRS9
DHRS9 isoform 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.939
DHRS3
Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
0.923
RETSAT
RETSAT isoform 1.
  
 
 0.923
CYP26A1
Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 
 0.922
CYP27C1
CYP27C1 isoform 1; Belongs to the cytochrome P450 family.
   
 
 0.918
BCO1
BCO1 isoform 1.
     
 0.912
DGAT1
O-acyltransferase.
   
 
 0.905
PNPLA4
PNPLA4 isoform 1.
   
 
 0.903
AWAT2
Acyl-CoA wax alcohol acyltransferase 2.
     
 0.902
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.