DIS3L protein (Pongo abelii) - STRING interaction network

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DIS3L

DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. (1053 aa)

Predicted Functional Partners:

EXOSC10

0.998

EXOSC1

0.998

EXOSC8

0.998

EXOSC7

0.998

EXOSC9

0.998

EXOSC3

0.998

EXOSC6

0.997

EXOSC5

0.997

EXOSC2

0.997

EXOSC4

0.996

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DIS3L	EXOSC1	ENSPPYP00000007457	ENSPPYP00000002937	DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.	Exosome component 1.	0.998
DIS3L	EXOSC10	ENSPPYP00000007457	ENSPPYP00000002191	DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.	EXOSC10 isoform 2.	0.998
DIS3L	EXOSC2	ENSPPYP00000007457	ENSPPYP00000022078	DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.	EXOSC2 isoform 3.	0.997
DIS3L	EXOSC3	ENSPPYP00000007457	ENSPPYP00000021356	DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.	Exosome component 3.	0.998
DIS3L	EXOSC4	ENSPPYP00000007457	ENSPPYP00000021264	DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.	EXOSC4 isoform 1.	0.996
DIS3L	EXOSC5	ENSPPYP00000007457	ENSPPYP00000011211	DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.	EXOSC5 isoform 1.	0.997
DIS3L	EXOSC6	ENSPPYP00000007457	ENSPPYP00000008518	DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.	Exosome complex component MTR3.	0.997
DIS3L	EXOSC7	ENSPPYP00000007457	ENSPPYP00000015600	DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.	EXOSC7 isoform 6.	0.998
DIS3L	EXOSC8	ENSPPYP00000007457	ENSPPYP00000006024	DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.	Exosome component 8.	0.998
DIS3L	EXOSC9	ENSPPYP00000007457	ENSPPYP00000016797	DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.	Exosome component 9.	0.998
EXOSC1	DIS3L	ENSPPYP00000002937	ENSPPYP00000007457	Exosome component 1.	DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.	0.998
EXOSC1	EXOSC10	ENSPPYP00000002937	ENSPPYP00000002191	Exosome component 1.	EXOSC10 isoform 2.	0.999
EXOSC1	EXOSC2	ENSPPYP00000002937	ENSPPYP00000022078	Exosome component 1.	EXOSC2 isoform 3.	0.998
EXOSC1	EXOSC3	ENSPPYP00000002937	ENSPPYP00000021356	Exosome component 1.	Exosome component 3.	0.999
EXOSC1	EXOSC4	ENSPPYP00000002937	ENSPPYP00000021264	Exosome component 1.	EXOSC4 isoform 1.	0.999
EXOSC1	EXOSC5	ENSPPYP00000002937	ENSPPYP00000011211	Exosome component 1.	EXOSC5 isoform 1.	0.999
EXOSC1	EXOSC6	ENSPPYP00000002937	ENSPPYP00000008518	Exosome component 1.	Exosome complex component MTR3.	0.999
EXOSC1	EXOSC7	ENSPPYP00000002937	ENSPPYP00000015600	Exosome component 1.	EXOSC7 isoform 6.	0.999
EXOSC1	EXOSC8	ENSPPYP00000002937	ENSPPYP00000006024	Exosome component 1.	Exosome component 8.	0.999
EXOSC1	EXOSC9	ENSPPYP00000002937	ENSPPYP00000016797	Exosome component 1.	Exosome component 9.	0.999

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