node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARL6IP1 | CR201_G0031384 | ENSPPYP00000008071 | ENSPPYP00000003548 | ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates a [...] | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 0.984 |
ARL6IP1 | FAU | ENSPPYP00000008071 | ENSPPYP00000003561 | ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates a [...] | Ubiquitin-like protein FUBI. | 0.984 |
ARL6IP1 | RPS11 | ENSPPYP00000008071 | ENSPPYP00000023489 | ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates a [...] | RPS11 isoform 3; Belongs to the universal ribosomal protein uS17 family. | 0.933 |
ARL6IP1 | RPS19 | ENSPPYP00000008071 | ENSPPYP00000011224 | ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates a [...] | 40S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family. | 0.926 |
ARL6IP1 | RPS20 | ENSPPYP00000008071 | ENSPPYP00000020858 | ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates a [...] | 40S ribosomal protein S20. | 0.930 |
ARL6IP1 | RPS29 | ENSPPYP00000008071 | ENSPPYP00000006576 | ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates a [...] | 40S ribosomal protein S29. | 0.927 |
ARL6IP1 | RPS3 | ENSPPYP00000008071 | ENSPPYP00000004215 | ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates a [...] | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...] | 0.930 |
ARL6IP1 | RPS3A | ENSPPYP00000008071 | ENSPPYP00000023498 | ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates a [...] | 40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. | 0.929 |
ARL6IP1 | RPS5 | ENSPPYP00000008071 | ENSPPYP00000024669 | ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates a [...] | RPS5 isoform 1; Belongs to the universal ribosomal protein uS7 family. | 0.925 |
ARL6IP1 | RPS9 | ENSPPYP00000008071 | ENSPPYP00000011623 | ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates a [...] | Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. | 0.928 |
CR201_G0031384 | ARL6IP1 | ENSPPYP00000003548 | ENSPPYP00000008071 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates a [...] | 0.984 |
CR201_G0031384 | FAU | ENSPPYP00000003548 | ENSPPYP00000003561 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | Ubiquitin-like protein FUBI. | 0.989 |
CR201_G0031384 | RPS11 | ENSPPYP00000003548 | ENSPPYP00000023489 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | RPS11 isoform 3; Belongs to the universal ribosomal protein uS17 family. | 0.999 |
CR201_G0031384 | RPS19 | ENSPPYP00000003548 | ENSPPYP00000011224 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 40S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family. | 0.999 |
CR201_G0031384 | RPS20 | ENSPPYP00000003548 | ENSPPYP00000020858 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 40S ribosomal protein S20. | 0.999 |
CR201_G0031384 | RPS29 | ENSPPYP00000003548 | ENSPPYP00000006576 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 40S ribosomal protein S29. | 0.998 |
CR201_G0031384 | RPS3 | ENSPPYP00000003548 | ENSPPYP00000004215 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...] | 0.999 |
CR201_G0031384 | RPS3A | ENSPPYP00000003548 | ENSPPYP00000023498 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. | 0.999 |
CR201_G0031384 | RPS5 | ENSPPYP00000003548 | ENSPPYP00000024669 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | RPS5 isoform 1; Belongs to the universal ribosomal protein uS7 family. | 0.991 |
CR201_G0031384 | RPS9 | ENSPPYP00000003548 | ENSPPYP00000011623 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. | 0.999 |